Immunology 7100-IMM-3-SJ

Lectures - prof. dr hab. Wiesław Deptuła:
Introduction to immunology, basic immunological concepts, microbiome and the immune system of mammals. Structure and ontogenesis of the immune system, blood and lymph vessels, central and peripheral lymphatic organs in mammals, including farm, laboratory and companion animals. Immune system cells including platelets in mammals and animals as above. Anatomical and physiological barriers, mechanisms of non-specific and specific cellular and humoral immunity in mammals and animals as above. Antigen pathway in the immune system, allergic reactions, immune diseases in mammals, and selected data from clinical veterinary immunology.

Labs dr hab. Wiesław Krumrych, assistant professor, mgr. inż. Henryk Kozłowski::
Organization of laboratory classes, laboratory regulations, health and safety regulations, introduction to immunology, among others organs of the immune system, functions, types of immunity etc.
Cells of the immune system and the functions of cells involved in non-specific immunity - the phagocytosis process and the killing ability of these cells, e.g. NBT, LZM, MPO, etc.
Assessment of specific cellular and humoral immunity - T and B lymphocytes and their products (cytometry, detection of antibodies and immune complexes). Enzyme immunoassays, their types, immunoprecipitation, Western blotting, immunodetection, immunocytochemical markers.

Total student workload

Hours carried out with the participation of teachers (60 hours) -30 hours lectures -30 hours laboratory classes (exercises) Time devoted to individual student work (40 hours) - preparation for assignments 30 hours - own work on studies - 5 hours - participation in consultations - 5 hours Total: 100 hours

Learning outcomes - knowledge

W1 - knows and can discuss the stages of the diagnostic procedure; K_W15 W2 - lists the structure of the immune system, its ontogenesis and describes non-specific cellular and humoral defense mechanisms as well as immunity and anti-infective resistance in animals (mammals), K_W04, W3 - knows and can discuss the stages of the immune response and the principles of non-specific and specific prophylaxis in animals (mammals); K_W24 W4 - lists and describes diseases with an immune basis, including autoimmune diseases in animals (mammals) K_W24

Learning outcomes - skills

U1 - is able to choose the appropriate methods to determine non-specific and specific cellular and humoral immunity in terms of the activity and number of selected indicators of these immunities as an element of the assessment of the immune status, mainly anti-infective in animals (mammals). , K_U04

Learning outcomes - social competencies

K1 - feels the need to constantly update knowledge; K_K08 K2 - understands the need to organize interpersonal cooperation in the laboratory; K_K09 K3 - understands the need to maintain safety rules when working with biological material. K_K01

Teaching methods

- presentation of information with the use of multimedia (lectures); - laboratory activities in the field of: evaluation of the activity and quantity of selected indices of specific indices of cellular and humoral immunity (laboratory classes - exercises).

Type of course

compulsory course

Prerequisites

Knowledge of the structure and functions of the circulatory and lymphatic systems and organs in animals (mammals), including thymus, bone marrow, spleen, lymph nodes (knowledge of Physiology and Anatomy). Knowledge of the endocrine system (hormones) and general biological knowledge are recommended. It requires manual and microscope skills, as well as the ability to read microscopic preparations, which results from the acquired skills of the Microbiology subject.

Course coordinators

Term 2021/22Z:

Wiesław Deptuła
Wiesław Krumrych

Term 2022/23Z:

Wiesław Deptuła
Wiesław Krumrych

Term 2023/24Z:

Wiesław Deptuła
Wiesław Krumrych
Sylwia Wrotek

Term 2024/25Z:

Wiesław Deptuła
Sylwia Wrotek

Assessment criteria

Assessment methods and criteria
- Written exam on the knowledge presented during lectures,
- Completion of laboratory classes through partial tests, including practical and final written tests. Attendance at laboratories is mandatory

Assessment criteria -
satisfactory grade: 60-70% of the maximum number of points,
satisfactory plus: 71-80% of the maximum number of points
good grade: 81-87% of the maximum number of points
good plus grade: 88-94% of the maximum number of points
very good: over 94% of the maximum number of points.

Practical placement

Not applicable

Bibliography

Basic literature:
1. Zarys immunologii ssaków. Wiesław Deptuła, Jan Buczek. Wydawnictwo Uniwersytetu Jagiellońskiego, 1998.
2. Immunologia porównawcza i rozwojowa zwierząt. Jan Buczek, Wiesław Deptuła, Zdzisław Gliński, Jan jarosz, Michał Stosik, Andrzej Wernicki, PWN, 2000
3. Immunologia fakty znane i nieznane. Wiesław Deptuła, Beata Tokarz-Deptuła, Ryszard K. Pisarski. Wydawnictwo Państwowej Wyższej Szkoły Zawodowej im. Witelona, 2014.
4. Immunologia. J. Gołąb, M. Jakóbisiak, W. Lasek, T. Stokłosa. Wyd. PWN, W-wa 2019.
5. Immunologia dla biologów. Wiesław Deptuła, Beata Tokarz – Deptuła, Michał Stosik. Uniwersytet Szczeciński 2008
6. Veterinary Immunology 10th edition, Ian Tizard, Elsevier, 2018.
7. Handbook of vetebrate immunology, Paul-Pierre Pastoret, Philip Griebel, Hervé Bazin André Govaerts, Academic Press, 1998
8. Veterinary clinical immunology, Halliwell and Gorman, W.B Saunders, 2019.
9. Atlas of immunology. J.M.Cruse, R.E.Lewis, CRC Press, Springer, 2015.
10. Veterinary Hematology. B.E. Feldman, J.G. Zinkl, N.C.Jain, Lippincott Williams & Wilkins 2000.
11. Immunochemia w biologii medycznej. Metody laboratoryjne. Red.: I. Kątnik-Prastowska, Wyd.PWN W-wa, 2009.
12. Immunologia Ryb. M. Stosik. W. Deptuła, Wyd. N. Uniwersytet Szczeciński, Szczecin 2001
13. Immunologia Weterynaryjna - Wybrane Zagadnienia. Red. A. K. Siwicki, W. Deptuła, Wyd. Uniwersytet Warmińsko-Mazurski, Olsztyn 2001
14. Wiśniewski J., Siwicki A.K., Wiśniewska M., Wprowadzenie do ogólnej i klinicznej immunologii weterynaryjnej, Wyd. Uniwersytet Warmińsko-Mazurski, Olsztyn 2004

Supplementary literature (magazines), i.a:
Medycyna Wet., Centr.Europ.J.Immunol., Postepy Mikrobiol., Postępy Hig. Med. Dośw., Postępy Bioch., Acta Bioch.Pol., Post. Biol. Kom., Nat.Rev. Immunol., etc

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 7100-IMM-3-SJ in USOSweb