Testing drugs in animal models 2600-S1-CM-PW7a-TL

The aim of the course is to familiarize the student with methods of testing drugs on animal models. Laboratory animals are used, among others, in genetic, pharmacological, physiological, oncological, hematological, and embryological research. Many structural and functional similarities with the human body predispose the use of animal models for testing drug effects. These similarities include genetic material, the course of physiological processes, and organ morphology

Total student workload

1. The time of classes conducted with the participation of instructors: 15 hours of lecture + 15 hours of laboratory i.e. 30 contact hours 2. The time devoted to self-study of a student: 20 hours 3. The time required to prepare for assessment and grading: 25 hours total student workload: 75 hours e.i. 3 ECTS

Learning outcomes - knowledge

The student knows the biology of model animals; the ethical principles of conducting research on animals; and the types of behavioral tests used to test the effects of drugs. K_W02, K_W03, K_W08

Learning outcomes - skills

Can select an animal model to test the effects of a specific drug. K_U01, K_U03, K_U04, K_U10

Learning outcomes - social competencies

Understands the importance of research on animal models for the development of therapies and treatment methods in humans. K_K04, K_K06

Course coordinators

Justyna Rogalska

Teaching methods

Lecture: multimedia presentation Laboratory exercises: planning and analyzing behavioral tests, working with specialized software

Observation/demonstration teaching methods

- display

Expository teaching methods

- informative (conventional) lecture

Exploratory teaching methods

- observation
- experimental

Type of course

elective course

Prerequisites

completed course in human physiology

Assessment criteria

Lecture completion: Attendance at lectures (up to 2 absences allowed)
Positive grade on the final colloquium

Laboratory completion:
Attendance at laboratory classes (up to 1 absence allowed)
Assessment of current preparation and activity during classes (30%)
Assessment of the report on the conducted experiment and its discussion (multimedia presentation)
Positive grade on the final colloquium (50%)

Grading criteria:
Required threshold for a passing grade: 55-60%
Satisfactory plus: 61-70%
Good: 71-80%
Good plus: 81-90%
Very good: 91-100%

Practical placement

N/A

Bibliography

The Behavior of the Laboratory Rat: A Handbook with Tests 1st Edition by Ian Q. Whishaw (Editor), Bryan Kolb (Editor); 2005; Oxford University Press
The Laboratory Rat by Krinke, Bullock, Bunton, 2000, Academic Press
Scientific journal publications

Notes

Term 2024/25Z:

None

Term 2025/26Z:

None

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 2600-S1-CM-PW7a-TL in USOSweb