Skin photobiology 2600-OG-BK-FS

The main goal of the course is to give the students a broad overview of the most important scientific fields of photobiology and photomedicine with a focus on photophysics and photochemistry, penetration of light in tissue, photomedicine including photodynamic therapy, photodiagnosis, UV effects on tissue (DNA damage, photocarcinogenesis, photoimmunology, UV cell signaling and vitamin D synthesis), photosynthesis, environmental photobiology and photosensory biology.
The lectures will focus on a general aspects of skin photobiology, photomedicine, photoneuroendocrine and photoimmunological aspects of skin biology. In addition the following topic will be studied: anatomy, histology and pathology of the skin, skin phototypes, methods for the detection of UV-induced changes in the skin, analysis of sunscreens and methods for detection of reactive oxygen species, artificial UV radiators (sunbeds, sunlamps, nail lamps).

Total student workload

(in Polish) Udział w zajęciach — 25 godz. Konsultacje — 10 godz. Samodzielna praca studenta: -Przygotowanie do zajęć, w tym gromadzenie danych do raportu — 20 godz. -Pisanie raportów końcowych — 25 godz. -Lektura literatury — 20 godz. Razem: 100 godz. (4 ECTS)

Learning outcomes - knowledge

Student W1: has basic knowledge of skin anatomy and histology and identifies the layers of the skin W2: possesses knowledge of the interaction of the skin with the nervous, endocrine and immune systems W3: possesses knowledge of potential of medical use of light W4: is familiar with the methods of skin photoprotection W5: possesses knowledge of positive and negative effects of skin exposured to UV W6: has advanced knowledge of photoimmunology and its medical aspects W7: possesses knowledge of physical, chemical and physiological basis of the influence of light radiation on chemical substances, cells, tissues (especially the skin) and the human body

Learning outcomes - skills

Student U1: has the ability to identify the active ingredients of sunscreens U2: can explain the mechanisms of damages induced by UV radiation U3: can explain the mechanism of natural protective mechanisms of skin against UV radiation (immediate and delayed tanning) U4: is able to pose a research problem and critically analyze scientific publications in the field of the impact of UV radiation on the skin

Learning outcomes - social competencies

Student K1: understands the significance of skin photoprotection K2: identifies the negative effects of UV radiation on the skin K3: understands the need for educate the society how to protect the skin against UV radiation K4: understands the significance of proper vitamin D serum level K5: is able to work in a multi-specialist team solving scientific and practical problems in the field of photobiology of the skin.

Course coordinators

Anna Brożyna

Teaching methods

Expository teaching methods: -informative lecture -discussion -participatory lecture Exploratory teaching methods - practical - experimental - laboratory - presentation of a paper

Observation/demonstration teaching methods

- display

Expository teaching methods

- discussion
- informative (conventional) lecture
- participatory lecture

Exploratory teaching methods

- practical
- laboratory
- presentation of a paper
- observation
- project work
- experimental

Prerequisites

Basic knowledge of biology.

Assessment criteria

Assessment methods:
- final report - W1, W2, W3, W4, W5, W6, W7, U1, U2, U3, U4, K4
- activity - U1, U2, U3, U4, K1, K2, K3, K4

Assessment criteria:

fail - <60%
satisfactory - 60-67%
satisfactory plus - 68-76%
good - 77-85%
good plus - 86-94%
very good - >94%

An 80% attendance rate is required.

Practical placement

not applicable

Bibliography

Andrzej T Slominski, Michal A Zmijewski, Cezary Skobowiat, Blazej Zbytek, Radomir M Slominski, Jeffery D Steketee: Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system, Adv Anat Embryol Cell Biol. 2012;212:v, vii, 1-115. doi: 10.1007/978-3-642-19683-6_1.
Rünger TM. Cutaneous Photobiology. In: Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AJ, Orringer JS. eds. Fitzpatrick's Dermatology, 9e. McGraw Hill; 2019. Accessed January 08, 2023. https://accessmedicine.mhmedical.com/content.aspx?bookid=2570§ionid=210416520
Calderhead, R. G. , & Tanaka, Y. (2017). Photobiological Basics and Clinical Indications of Phototherapy for Skin Rejuvenation. In (Ed.), Photomedicine - Advances in Clinical Practice. IntechOpen. https://doi.org/10.5772/intechopen.68723
Antony R Young, Joël Claveau, Ana Beatris Rossi: Ultraviolet radiation and the skin: Photobiology and sunscreen photoprotection,
J Am Acad Dermatol. 2017 Mar;76(3S1):S100-S109.
doi: 10.1016/j.jaad.2016.09.038

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 2600-OG-BK-FS in USOSweb