Molecular basis of cell signaling 2600-MBCBIOT-SX-S2

General principles of cell signaling
Communication in single-cell organisms
Signal transduction in animals
Cell membrane as a medium in signaling
Types of cell signaling
Stages of cell signaling
Signaling molecules (primary and secondary)
Signaling receptors
Diseases in signaling
Effects of disfunction of cellular communication

Total student workload

Contact hours with the teacher - participation in lectures – 15h Student self-education – preparation for passing the final test – 35h Total number of hours: 50 hours (2 ECTS)

Learning outcomes - knowledge

W1 – Understanding the principles of signal transduction between cells – K_W01, K_W03, K_W09 W2 – Being able to give examples of different types of signaling molecules, and describing their structure and mechanism of action – K_W01, K_W03, K_W09 W3 – Classifying receptors, based on their structure, properties and mechanism of activation by their respective ligands – K_W01, K_W03, K_W09 W4 – Being able to describe diseases related to disturbances in proper signal transduction – K_W01, K_W03, K_W09

Learning outcomes - skills

U1 – Is able to critically refer to information obtained from literature sources – K_U02, K_U04 U2 – Is able to use English-language literature sources – K_U03

Learning outcomes - social competencies

K1: Understanding the need to deepen knowledge and develop skills – K_K01, K_K04 K2: Awareness of the emergence of new technologies in the field of neuroscience – K_K10

Course coordinators

Ákos Nemecz
Dorota Nemecz

Teaching methods

Informative lecture (conventional) with multimedia presentation

Expository teaching methods

- participatory lecture
- informative (conventional) lecture

Type of course

elective course

Prerequisites

Prerequisites include a basic course in biochemistry and cell biology

Assessment criteria

Written assessment in the form of a test composed of multiple-choice and open questions (in English).
The condition for admission to the test is class participation.

Grading criteria:
satisfactory grade: 60-70% of the maximum number of points, satisfactory plus grade: 71-80% of the maximum number of points good grade: 81-87% of the maximum number of points
good plus grade: 88-94% of the maximum number of points
very good grade: above 94% of the maximum number of points

Practical placement

Not applicable

Bibliography

Basic literature:
- Biochemistry, Stryer L, Tymoczko JL, Berg JM (2015), WH Freeman
- Lehninger Principles of Biochemistry, Nelson and Cox (2021), WH Freeman

Supplementary literature:
Scientific publications covering the topics discussed during the lectures

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 2600-MBCBIOT-SX-S2 in USOSweb