(in Polish) Cytotoxicity evaluation of chemical compounds 2600-DM-CE-2-S2

(in Polish) Contact hours (32 h): - lectures - 10 h - laboratory classes – 20 h - consultations with teacher - 2 h Student's individual work (68 h): - preparation to laboratory classes – 8 h - writing projects and reports – 10 h - repetition and extended study - 20 h - preparation to pass the lab test - 10 h - preparation to pass the final test – 20 h Total time 100 h = 4 ECTS

(in Polish) W1: Student describes the important concepts and processes in biochemistry, cell biology and toxicology K_W01, K_W08, K_W15 W2: Student demonstrates the knowledge on selected cytotoxic agents and characterizes methods of their identification and evaluation such as viability or survival tests, assays based on cell proliferation, metabolic activity, microtitration assays and drug interactions K_W02, K_W11 W3: Student uses the terminology specific for toxicology and defines: viability, toxicity, survival, tissue and systemic responses, genotoxicity, and inflammation response K_W02, K_W06 W4: Student defines the research hypothesis and can choose adequate methods/procedures to solve the scientific problem related to detection of potential cytotoxic effect(s) K_W11, K_W12, K_W17, K_W21 W5: Student has the knowledge on preparation of presentations, reports, documentation and evaluation of obtained results, can draw correct conclusions K_W20

(in Polish) U1: Student has the ability to work individually or in a group K_U02 U2: Student uses the knowledge on structure and properties of biomolecules and molecular markers to diagnostic analyses K_U04, K_U05, K_U10 U3: Student uses specialist terminology and biological nomenclature and specialized terms in biochemistry, biotechnology and toxicology K_U13 U4: Student recognizes the possibilities and limitations of molecular diagnostics techniques in cytotoxicity assays K_U10, K_U11, K_U12 U5: Student applies the correct and suitable cytotoxicity assay to determine potential cytotoxicity of compounds being studied K_U05, K_U12 U6: Based on the analyzes and experiments performed, student identifies the effects of cytotoxic influence at the cellular, tissue, organ and whole organism level K_U17, K_U19 U7: Student interprets correctly obtained results, draws the final conclusions and can prepare reports, laboratory documentation and expert presentations using correct scientific and technical terminology K_U13, K_U14

(in Polish) K1: Student understands that the lifelong learning is the ongoing, voluntary and self-motivated pursuit of knowledge for either personal or professional reasons K_K05 K2: Student is aware of the responsibility of his work as diagnostic professional and takes care of developing the positive image of this profession K_K08 K3: Student can work in a team and/or coordinate the work of research group K_K09 K4: Student can critically evaluate the obtained results K_K10

(in Polish) Lecture: informative lecture Laboratory classes: students (2-3 persons in a team) have to perform the analyses according to the obtained protocol. The experiments have to be conducted in aseptic conditions therefore lab groups should be as small as possible (max. 8-10 persons).

- informative (conventional) lecture
- problem-based lecture

- laboratory
- experimental
- project work
- observation
- practical

(in Polish) Basic knowledge in biochemistry, in vitro cell culture and cytophysiology.

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

• Description of 2600-DM-CE-2-S2 in USOSweb