Biomedical and Humanistic Basis of Pharmacy: Biochemistry
1755-F2-BCHEML-J
Biochemistry is the basic science for all biological disciplines. The aim of teaching of this subject is to present basic knowledge about the structure of biomolecules and their metabolism, with particular regard to the following issues: 1) connection between proteins conformation and their biological activity; 2) obtaining energy in metabolic processes and its storaging; 3) biosynthesis of macromolecules precursors; 4) metabolism integration; 5) basis of molecular genetics.
During the laboratory tutorials students will get acquainted with the chemical structure of particular compounds, which build living organism, and their properties, as well as quantification and identification methods.
Lectures will deliver knowledge about metabolism of these compounds, methods of regulation and metabolic profile of the most important organs.
Total student workload
1. Obligatory hours realized with the teacher participation
- Lecture participation – 30 hours
- Tutorials participation – 65 hours,
- consultations participation, including scientific and research consultations – 13 hours,
- final exam participation – 2 hours
Total obligatory hours realized with the teacher participation: 110 hours, which corresponds to 4.4 ECTS point.
2. Student workload balance:
- lecture participation – 30 hours,
- laboratories participation – 65 hours,
- consultations participation, including scientific and research consultations – 13 hours,
- reading the indicated literature – 15 hours,
- preparation for laboratories – 15 hours,
- preparation for test – 15 hours,
- preparation for final exam – 20 hours,
- final exam participation – 2 hours
A total work amount: 175 hours, which corresponds to 7 ECTS point.
3. Workload related to conducting research:
- reading the indicated literature -10 hours,
- participation in lectures (including methodology of research, research results and scientific studies)- 20 hours,
- participation in research-scientific consultations- 5 hours,
- participation in laboratories including scientific results: 30 hours,
- preparation for laboratories including scientific results: 15 hours,
- preparation for final exam including research results and scientific studies in the field of realized subject – 20 hours.
A total student workload related to the conducted research is 100 hours, which corresponds to 4.0 ECTS point.
4. Time required for the preparation and participation in evaluating process:
- preparation for test – 15 hours,
- preparation for final exam and taking part in exam– 20+2 = 22 hours
Total time required for preparation and participation in evaluating process: 37 hours, which corresponds to 1,48 ECTS point.
5.Time required for the practical training completion – not applicable.
Learning outcomes - knowledge
Students:
W1: Knows and understands the structure and biological role of carbohydrates, lipids, amino acids, proteins, nucleic acids, hormones and vitamins (K_A.W8).
W2: Knows the types and subtypes of lipids and proteins forming biological membranes (K_A.W9). Knows and understands the structure and functions of membrane channels and mechanisms associated with transport across biological membranes (K_A.W9).
W3: Knows and understands the mechanisms of signal transduction between cells, as well as between the cell and extracellular matrix (K_A.W10).
W4: Knows and understands metabolic processes and regulatory strategies at the molecular, cellular, organ and systemic levels (K_A.W11)
Learning outcomes - skills
Student:
U1: Is able to use biochemical knowledge to assess physiological and pathological processes occurring in cells and at the level of the whole organism (K_A.U6).
U2: Is able to detect and determine amino acids also using thin layer chromatography (K_A.U7).
U3: Is able to detect, fractionate and determine proteins using chromatographic techniques and the biuret method (K_A.U7).
U4: Is able to perform the characteristic reactions for simple sugars, disaccharides and polysaccharides (K_A.U7).
U5: Can detect and determine cholesterol and vitamins in biological material (K_A.U7).
U6: Can obtain RNA from yeasts cells (K_A.U7).
U7: Is able to determine the concentration of nucleic acids and assess their purity after isolation (K_A.U7).
U8: Is able to perform kinetic studies of invertase enzymatic reactions using the reaction of sugars with 3,5-dinitrosalicylic acid (DNS) (K_A.U8).
Learning outcomes - social competencies
Student:
K1: Is ready to draw conclusions from quantitative and qualitative determinations made during biochemistry classes (K8).
Teaching methods
Lecture:
informative lecture supported by multimedia techniques,
problem lecture with multimedia presentation,
Laboratory tutorials:
laboratory method, observation, demonstration, exercise method
Expository teaching methods
- discussion
- description
- informative (conventional) lecture
Exploratory teaching methods
- practical
- seminar
- laboratory
Prerequisites
Students should have the basic knowledge in the field of general chemistry, organic chemistry and biology.
Course coordinators
Assessment criteria
Laboratory tutorials;
- Written test: short test of written information at the beginning of the exercise W1-W4, U1-U8, K1: (0-4 points; pass threshold ≥ 60%)
- Practical performance of tutorials: Active participation in tutorials :U1,-U7, K1, (0-2 points)
3 Written tests: passing a grade based on a test (the written test consists of single-choice closed questions and open-ended questions) from knowledge gained during lectures, laboratories and exercises. To obtain a positive assessment, it is necessary to get 60% of points.
Number of points Grade
29-30 Excellent (5.0)
27-28 Very good (4.5)
24-26 Good (4.0)
21-23 Satisfactory (3.5)
18-20 Acceptable (3.0)
0-17 Fail (2.0)
Exam:
The final theoretical exam consists of 50 test questions (single choice answer) regarding the knowledge acquired during lectures, laboratories and exercises.
Exam: (0 - 50 points; pass threshold ≥ 60%)
Number of points Grade
47-50 Excellent (5.0)
43-46 Very good (4.5)
39-42 Good (4.0)
35-38 Satisfactory (3.5)
30-34 Acceptable (3.0)
0-29 Fail (2.0)
Practical placement
Not applicable according to the educational program
Additional information
Additional information (registration calendar, class conductors,
localization and schedules of classes), might be available in the USOSweb system: