Pharmacology and Pharmacodynamics
1724-F3-FARMF-L-J
The course will prepare students to learn subsequent professional subjects by acquiring knowledge about the mechanisms responsible for the absorption and action of drugs in the body. The topics of the classes will include physiological factors influencing the fate of drugs in the body, mechanisms of drug action, issues related to receptors and receptor theories, drug-specific and dose-dependent side effects, drug-induced diseases, secondary side effects; allergic and pseudo-allergic reactions, drug interactions, side effects of drugs in various periods of pregnancy, postpartum and breastfeeding; bioavailability and bioequivalence of drugs. During the course, students also learn experimental methods in pharmacology and the principles of conducting preclinical and clinical research. Based on the general knowledge of pharmacology, students become familiar with drugs used in the chemotherapy of infections and invasive diseases: β-lactam antibiotics, aminoglycoside antibiotics, tetracyclines, chloramphenicol, macrolide antibiotics, ketolides, lincosamides, streptogramins, peptide antibiotics, rifamycins, glycopeptide antibiotics, fusidic acid, derivatives ocasolidinone and mupirocin.
Total student workload
1. Obligatory hours realized with the teacher participation
- Lecture participation – 30 hours
- Tutorials participation – 15 hours
- Scientific-research consultation participation (discussion of scientific literature, development and interpretation of obtained research results, supplementing knowledge on the assessment of the therapeutic effect of drugs, personalized therapy, monitoring of treatment, drug interactions and side effects, "case study") - 4 hours
Total amount of work requiring academic teacher participation is 49 hours, which corresponds to 1.96 ECTS points
2. Time spent by the student on the individual work:
- Lecture participation – 30 hours,
- Tutorials participation – 15 hours,
- Scientific-research consultation participation – 2 hours,
- Preparation for classes – 10 hours,
- Preparation for colloquium – 8 hours
- Preparation for completion of the subject- 8 hours
- Reading the indicated scientific literature – 2 hour
Total amount of student individual work is 75 hours, which corresponds to 3 ECTS points
3. Time spent on scientific research:
- Reading the indicated scientific literature – 2 hour,
- Lecture participation (including research methodology, research results, reports) – 18 hours,
- Scientific-research consultations – 2 hour,
- Scientific practical classes participation (including research methodology, research results, reports) – 8 hours,
- Preparation for scientific practical classes – 5 hours,
- Preparation for completion of the subject in the field of scientific aspects- 5 hours
Total amount of work spent on scientific research is 40 hours, which corresponds to 1.60 ECTS points
4. Time required for the preparation and participation in evaluating process:
- Preparation for classes – 10 hours,
- Preparation for colloquium – 8 hours
- Preparation for completion of the subject- 8 hours
The total amount of work required for the preparation and participation in evaluating process is 26 hours, which corresponds to 1.04 ECTS points
5. Time required for the practical training completion – not applicable.
Learning outcomes - knowledge
W1: Knows the target points and mechanisms of drug action including the achievement of structural biology in this field - K_D.W12
W2: Knows the division and pharmacological properties of known drug groups -K_D.W13
W3: Knows the determinants of drug action in the pharmacodynamic phase, taking into account the hereditary factors of molecularly targeted therapy and drug resistance mechanisms - K_D.W14, K_D.W15
W4: Characterizes the route of administration, indicating the differences between them affecting pharmacotherapy, skillfully distinguishes drug dosing methods and is able to explain the assumptions of personalized therapy - K_D.W14- K_D.W16
W5: Knows the concepts of indications, contraindications and drug-specific and dose-related adverse reactions Understands the classification of adverse reactions - K_D.W18- K_D.W17
W6: Knows and understands the concepts of polypragmasia as well as the principles of proper drug pairing and the possibility of drug interactions occurring and avoiding, - K_D.W19
W7: Knows the basic concepts of pharmacogenetics and pharmacogenomics and is aware and familiar with new developments in the field of pharmacology - K_D.W20
Learning outcomes - skills
U1: Is able to specify the causes and effects of drug interactions and interprets the impact of factors on drug action - K_D.U9
U2: Can explain the pharmacological properties of the drug based on the target point and mechanism of action - K_D.U11
U3: Is able to propose the necessity to change the drug dosage resulting from physiological and pathological conditions as well as genetic factors - K_D.U12
U4: Can capture the possibility of adverse effects of individual groups of drugs depending on the dose and mechanism of action - K_D.U13
U5: Is able to notice the possibility of side effects, determine their causes and effects in the pharmacodynamic phase and determine ways to prevent these interactions - K_D.U14
U6: Independently constructs information necessary to provide the patient with indications and contraindications for the use of drugs and in the scope of their proper dosage and intake - K_D.U15
U7: Is able to present information on pharmacology in a way understandable to the patient - K_D.U16
U8: Is able to establish interpersonal contacts necessary in contacts with representatives of other medical professions in the scope of ensuring safety and effectiveness of pharmacotherapy - K_D.U17
U11: prevents interactions in the pharmacokinetic phase - K_D.U10
U12: cooperates in ensuring the safety and effectiveness of pharmacotherapy - K_D.U15
U13: provides information on the mechanism of action, pharmacological properties and side effects of the drug - K_D.U13
U14: predicts the occurrence of an adverse drug reaction - K_D.U13
U15: prevents interactions between drugs and between drugs and food - K_D.U29
U16: monitors side effects of drugs - K_D.U13
U17: conveys the acquired knowledge in the field of pharmacology in a way understandable to the patient - K_D.U16
Learning outcomes - social competencies
K1: has the habit of working in an atmosphere of camaraderie, trust and mutual assistance - K_K1, K3
K2: draws and formulates conclusions from own measurements and observations - K_K8
K3: has the ability to work in a team, cares for the safety of themselves and others -K_K10
Teaching methods
Lecture:
Informative lecture with multimedia presentation
Problem-based lecture
Tutorials:
Assisted learning with the elements of multimedia presentation
Discussion of scientific literature
Problem-based learning
Expository teaching methods
- description
- informative (conventional) lecture
- problem-based lecture
- discussion
Exploratory teaching methods
- practical
- presentation of a paper
- case study
- observation
- seminar
- classic problem-solving
Type of course
compulsory course
Prerequisites
(in Polish) Do realizacji opisywanego przedmiotu niezbędne jest posiadanie podstawowych wiadomości z zakresu anatomii, fizjologii, biologii, biochemii, chemii analitycznej.
Course coordinators
Term 2023/24L: | Term 2024/25L: | Term 2022/23L: | Term 2025/26L: |
Assessment criteria
The basis for passing the course Pharmacology and Pharmacodynamics is compliance with the principles set out in the Teaching Regulations of the Department and Department of Pharmacodynamics and Molecular Pharmacology.
Lectures:
Admission to the lecture colloquium is based on the obligatory presence at lectures. The colloquium consists of test questions (closed one-choice answer as well as open answer) in the field of knowledge acquired during lectures. The student scores one point for every correct answer. To pass the lectures 60% of points are necessary.
Tutorials:
Admission to the tutorials colloquium is based on the obligatory presence at tutorials. The colloquium consists of test questions (closed one-choice answer as well as open answer) in the field of knowledge acquired during lessons. The student scores 1 point for every correct closed answer, respectively 2 points for every correct open answer. 60% of all points are required to pass the colloquium.
Both colloquiums (lectures and tutorials) are assessed on the basis of the same grading scale:
percentage of points grade
90-100% Excellent (5)
85-89% Very good (4.5)
80-84% Good (4)
75-79% Satisfactory (3.5)
60-74% Acceptable (3)
0-59% Fail (2)
Passing for grade in semester VI: the final grade for the course is calculated from the arithmetic mean of the grades obtained from colloquiums from lectures and exercises.
Practical placement
Not applicable according to the educational program
Bibliography
Primary literature:
1. Laurence Brunton, Bruce Chabner, Björn Knollmann; „Goodman & Gilman’s: The Pharmacoplogical Basis of Therapeutics”
2. Bertram Katzung, Susan Masters, Anthony Trevor Basic and Clinical Pharmacology.
3. James Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEwan, Humphrey Rang - Rang & Dale’s Pharmacology.
Supplementary literature:
1. Ernst Mutschler and Hartmut Derendorf, Drug Actions; Basic Principles and Therapeutic Aspects.
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Term 2025/26L:
Primary literature:
1. Laurence Brunton, Bruce Chabner, Björn Knollmann; „Goodman & Gilman’s: The Pharmacoplogical Basis of Therapeutics”
2. Bertram Katzung, Susan Masters, Anthony Trevor Basic and Clinical Pharmacology.
3. James Ritter, Rod Flower, Graeme Henderson, Yoon Kong Loke, David MacEwan, Humphrey Rang - Rang & Dale’s Pharmacology.
Supplementary literature:
1. Ernst Mutschler and Hartmut Derendorf, Drug Actions; Basic Principles and Therapeutic Aspects.
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Additional information
Additional information (registration calendar, class conductors,
localization and schedules of classes), might be available in the USOSweb system: