Pharmacology and Toxicology 1655-Lek3FARM-J

The basic areas of the subject include: - discussion of indications for therapy and dosage in particular diseases - side effects of drugs - contraindications to pharmacotherapy - monitored therapy, pharmacoeconomics and drug resistance - toxicological aspects of particular groups of drugs The subject is carried out in the form of lectures, seminars and exercises. The topics of the lectures extend the scope of the material carried out at seminars and exercises.

Seminars/exercises
1. Introduction to pharmacokinetics and pharmacodynamics.
2. Prescriptions and formula.
3. Receptor theory. Drugs acting on the sympathetic nervous system (phantoms).
4. Receptor theory. Drugs acting on the sympathetic nervous system part 2.
5. Drugs acting on the parasympathetic nervous system. Skeletal muscle relaxants.
6. Colloquium number 1 + Pharmacotherapy of lipid disorders.
7. Anticoagulants, antiplatelet drugs, thrombolytics - current guidelines. Antiarrhythmic drugs.
8. Pharmacotherapy of hypertension.
9. Pharmacotherapy of diabetes. Pharmacotherapy of obesity.
10. Colloquium number 2 + Antihistamines, GKS/MCS.
11. Pharmacotherapy of pain - NSAIDs, opioids.
12. Pharmacotherapy in endocrinology (hypothalamus, pituitary, adrenal glands, pancreas, gonads).
13. Neuropharmacology: Pharmacotherapy of depression.
14. Neuropharmacology: Pharmacotherapy of AD, PD, MS.
15. Neuropharmacology: Schizophrenia, epilepsy.
16. Colloquium number 3 + General and local anesthesia.
17. Digestive system.
18. Antibiotics.
19. Antifungal and antiviral drugs, parasites.
20. Colloquium number 4 + Immunosuppressive drugs. PDE inhibitors Nitrates.
21. Addictions.
22. General and specific toxicology. The effect of drugs on laboratory test results.
23. Interactions.
24. Colloquium number 5 + colloquium number 6 (formula in practical form).

Total student workload

1. Obligatory hours carried out with the participation of the teacher: - participation in lectures – 38 hours - participation in seminars – 40 hours - participation in exercises – 40 hours - carrying out the assessment - 2 hours The workload related to classes requiring the direct participation of academic teachers is 120 hours, which corresponds to 4.8 ECTS points 2. Balance of student workload: - participation in lectures - 38 hours - participation in seminars - 40 hours - participation in exercises – 40 hours - preparation for and carrying out the assessment: 90 + 2 = 92 hours The total student workload is 210 hours, which corresponds to 7 ECTS points 3. Workload related to scientific research: - reading selected scientific literature: 20 hours - participation in lectures (taking into account research results and scientific studies in the field of pharmacology): 20 hours - participation in seminars (taking into account the results of scientific studies in pharmacology): 20 hours - preparation for passing the exam (including scientific studies in the field of pharmacology): 40 hours The total student workload related to research is 100 hours, which corresponds to 4 ECTS points. 4. Time required to prepare for and participate in the assessment process: - preparation for passing: 90 + 2 = 92 hours (3.68 ECTS points) 5. Balance of the student's practical workload: - participation in exercises – 40 hours The student's total practical workload is 40 hours, which corresponds to 1.6 ECTS points 6. Time required to complete mandatory internship – not applicable.

Learning outcomes - knowledge

W1: Explains the overall effect of drugs on the body, taking into account the mechanism of action, metabolism, indications and side effects taking into account age (C K_W34, C K_W35, C K_W36) W2: Characterizes the principles of pharmacotherapy, taking into account indications, side effects and drug interactions (C K_W37, C K_W38) W3: Explains the concepts of drug resistance, pharmacoeconomics, monitored therapy (C K_W39, E K_W40, E K_W41)

Learning outcomes - skills

U1: Estimates the risk of pathological phenomena, taking into account side effects and interactions, and selects optimal drugs and their doses (C K_U14, E K_U17) U2: He can write a prescription (C K_U16) U3: Can individualize therapy in selected cases (E K_U18)

Learning outcomes - social competencies

K1: is willing to improve competences and solve problems related to the profession (K_K08)

Teaching methods

Lectures: • information lecture • problem lecture • seminar lecture Seminars / Exercises: • didactic discussion • decision tree • case studies

Expository teaching methods

- discussion
- informative (conventional) lecture
- problem-based lecture

Exploratory teaching methods

- seminar

Prerequisites

The student knowledge of physiology and pathophysiology in the scope of classes from previous years of studies is required.

Course coordinators

Michał Wiciński

Assessment criteria

Oral or written test (0 - 60 points;> 60%): W1 -W3, U1, U3
Final examination in the oral or written form (0 - 60 points;> 60%): W1 -W3, U1, U3, K1

During tutorials and seminars, students are required to be familiar with the material from the previous seminar and tutorial topics.
Knowledge may be assessed orally or in writing.
Failure to pass a tutorial or seminar will result in ineligibility for the final exam. Make-up classes with another group may be arranged with the Department Head – limited space is available.

% of points obtained Assessment
92≤… ..≤100 Very good (5)
88≤… .. <92 Good plus (4+)
80≤… .. <88 Good (4)
71≤… .. <80 Sufficient plus (3+)
60≤… .. <71 Sufficient (3)
0… .. <60 Insufficient (2)

Practical placement

Not applicable

Bibliography

Basic literature:
1. Katzung's Basic & Clinical Pharmacology, Katzung, 16th Edition, 2023 (current edition).

Additional literature:
1. Rang & Dale’s Pharmacology, Rang & Dale, 10th edition, 2023 (current edition).
2. Harrison's Principles of Internal Medicine, Harrison, 22nd edition, 2025 (current edition).
3. McMaster Textbook of Internal Medicine 2019/2020, 2019 (current edition).

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 1655-Lek3FARM-J in USOSweb