3. Module: Haematopoietic System Diseases
1600-LekM3CUK-J
I. Topic of classes: seminars: 1. Anemia due to decreased red blood cell production: anemia due to iron deficiency, anemia due to lack of vitamin B12 and folic acid, anemia in chronic inflammations- diagnosis, clinical picture and treatment (2h). 2. Hemolytic and aplastic anemia- diagnosis, clinical picture and treatment (1h). 3. Myeloproliferative neoplasms: chronic myelogenous leukemia, polycythemia vera, essential thrombocythemia and primary myelofibrosis- diagnosing criteria, clinical picture, treatment (2h). 4. Hodgkin's lymphoma- histological classification, clinical picture, treatment (1h). 5. Non-Hodgkin lymphomas- 2008 WHO classification, prognostic factors, diagnosis and principles of treatment, detailed characteristic of most frequently diagnosed NHL: diffuse large B-cell lymphoma, follicular lymphoma, marginal zone lymphoma, mantle cell lymphoma, Burkitt lymphoma (2h). 6. Hemorrhagic diatheses related to plasma: A and B hemophilia, von Willebrand disease- clinical picture, diagnosis, treatment (2h). 7. Hemorrhagic diatheses related to platelets: immune thrombocytopenic purpura, thrombotic thrombocytopenic purpura, haemolytic-uraemic syndrome- pathogenesis, clinical picture, treatment (1h). tutorials 1. Acute myeloid leukemia and lymphoblastic leukemia in adults- WHO classification, clinical picture, chemotherapy and auxiliary therapy (3h). 2. Chronic lymphocytic leukemia: chronic lymphocytic leukemia (CLL), B-cell prolymphocytic leukemia (PLL), hairy cell leukemia- diagnosis, prognostic factors, clinical picture, methods of treatment (2h). 3. Myelodysplastic syndrome- pathogenesis, WHO classification, prognostic index, medical procedures (3h). 4. Myeloma multiplex- definition, diagnosis, clinical picture and treatment (3h). 5. Lymphadenopathy and splenomegaly (2h). Material for students to prepare independently. 1. Basis of hematopoiesis and hematological diagnostics. 2. Hemorrhagic diatheses congenital and acquired. 3. Basis of transfusion medicine. 4. Transplantation of hemapoietic stem cells- basic information.
Total student workload
1. Hours including teachers participation: 30 hours (15 hours of semminars and15 hours of practicals) = 0,2 ECTS.
2. The module includes 3 subjects: hematology, blood pathology (6 semminars), blood donation and haemotherapy (6 lectures).
3. Student's individual study time: 25 hours = 1 ECTS.
4. Time for test preparation: 25 hours = 1 ECTS.
5. Time required for summer practice: not applicable.
Learning outcomes - knowledge
Student: W1: has basic/ advanced knowledge of hematooncological diseases. W2: knows and understands the causes, symptoms, and principles of diagnosis and treatment of the most common haematopoietic diseases, including: bone marrow aplasia, anaemia, granulocytopenia and agranulocytosis, thrombocytopenia, acute leukaemia, myeloproliferative and myelodysplastic- myeloproliferative neoplasms, myelodysplastic syndrome, mature B and T cell neoplasms, haemorrhagic diathesis, thrombophilia, life-threatening emergencies in haematology, blood disorders in diseases of other organs, W3: is familiar with basic hematological disorders W4: is acquainted with treatment criteria of hematooncological diseases. W5: knows and understands the causes, symptoms, principles of diagnosing and therapeutic procedures in the most common problems of palliative medicine in neoplastic diseases of the hematopoietic system W6: knows the principles of blood therapy, indications for the use of blood products and the most common post-transfusion complications W7: knows the types of biological materials used in laboratory
diagnostics, the principles of collecting material for research and methods of microbiological, immunophenotype, genetic and histopathological examination W8: knows the environmental and epidemiological conditions of the most common diseases of the hematopoietic system
Learning outcomes - skills
Student: U1: is able to/ has the ability to perform a full and targeted physical examination of an adult patient U2: is capable of perform a medical interview with an adult patient U3: has basic/ advanced skills in differential diagnosis of hematooncological diseases U4: can analyze basic hematological disorders based on a morphology and biochemistry lab results
Learning outcomes - social competencies
Student: K1: is aware of own limitations and is able to pursue continuing education K2: understands the need for showing respect to patients and an understanding of worldview and cultural differences K3: is open to/ well prepared to cooperate with representatives of other healthcare professions K4: has the habit of and skills related to pursuing continuing education K5: identifies/ accepts/ recognizes … K6: participates in observing medical confidentiality and other patient rights (including the right to information, intimacy, informed decision, dignified dying) K7: can cooperate/ communicate/ work with other students
Teaching methods
Seminars: · Informative lecture · Clinical cases Practical classes: · practice
Expository teaching methods
- discussion
- participatory lecture
Type of course
compulsory course
Prerequisites
1. Ability to / communicate/ work with other students . 2. Capacity of performing a medical interview with an adult patient. 3. Knowledge of basic hematological disorders. 4. Ability to make a differential diagnosis between hematological diseases. 5.Acquaintance with treatment criteria of hematooncological diseases. 6. Ability to analize morphology and biochemistry lab results.
Course coordinators
Assessment criteria
Assessment methods: test W1-W8, U3, U4, K4 Assessment criteria: fail –<15pts (<75%) satisfactory –15pts (75%) satisfactory plus –16pts (80%) good –17pts (85%) good plus –18pts (90%) very good –19-20 pts (95-100%)
Practical placement
Bibliography
1. Harrison’s Hematology and Oncology 2016. Dan L. Longo
2. Hoffbrand's essential haematology / A. Victor Hoffbrand, Paul A.H. Moss. 2016. Seventh edition
Additional information
Additional information (registration calendar, class conductors,
localization and schedules of classes), might be available in the USOSweb system: