(in Polish) Spektroskopowe metody interpretacji struktury związków 0600-S2-O-SMISZ
Lecture:
The lecture aims to familiarise students with spectroscopic methods used in chemistry (electron and fluorescence spectroscopy of complex compounds, circular dichroism, nuclear magnetic resonance (2D, 15N NMR spectra), mass spectrometry)) and with the basic techniques necessary for their practical application. Issues from chemistry will illustrate the discussed theoretical issues. They will help to understand the versatility of using spectroscopic methods. Most of the examples discussed will show spectroscopy's applications in chemical sciences.
Lectures are organised to present the necessary theoretical foundations of a given phenomenon, followed by examples illustrating its application to study specific problems.
Program content of the lecture
• characteristics of electromagnetic radiation.
• basic types of molecular spectroscopy.
• mass spectrometry
• Jabłoński scheme.
• determination of terms for pn and dn configurations.
• energy ordering of terms and their degeneration.
• splitting terms with octahedral symmetry and construction of Tanabe-Sugano diagrams.
• interpretation of electronic spectra of complex compounds.
• electronic configurations and symmetry of ground and excited states.
• knowledge of the symmetry of the dipole moment operator and the symmetry of the excited state.
• reasons for registration of band gaps in the spectrum.
• introduction to 15N NMR spectrometry and 2D NMR spectra (examples of using spectroscopy to solve structural problems).
• comparison of the usefulness of various spectroscopic methods for solving structural problems.
Laboratory
The classes will allow students to acquire practical analysis skills of spectra and propose compounds’ structures based on spectroscopic parameters. Applying the acquired theoretical knowledge will allow for the independent solving of structural problems of macromolecules, e.g. proteins, nucleic acids, lipids and their interaction with inorganic drugs (e.g. anti-cancer drugs).
Program content Laboratory:
1. Application of mass spectrometry to the analysis of compounds.
2. Application of NMR spectroscopy for the analysis of compounds.
3. Identification of compounds based on their fluorescent properties.
4. Analysis and registration of electronic spectra of coordination compounds.
5. Interpretation of the structure of compounds based on IR, UV-Vis, NMR and MS spectra.
Total student workload
Learning outcomes - knowledge
Learning outcomes - skills
Learning outcomes - social competencies
Teaching methods
Expository teaching methods
- participatory lecture
- problem-based lecture
Exploratory teaching methods
- classic problem-solving
Online teaching methods
- content-presentation-oriented methods
Type of course
Prerequisites
Course coordinators
Term 2023/24L: | Term 2024/25L: | Term 2022/23L: |
Assessment criteria
Written exam (60%), laboratory (40%).
Lecture
Effects: K_W01, K_W02, K_W07, K_U01, K_U08, K_U09,
K_U11, K_U13, (K_K02, K_K03, K_K05, K_K07)
Required grade threshold:
- sufficient: 50 -60%
- sufficient plus: 61 - 65%
- good: 66 – 75%
- good plus: 76 – 80%
- very good: 81-100%
Laboratory:
(K_W01, K_W02, K_W07, K_W08, K_W12, K_U01, K_U08, K_U09, K_U11, K_U13, K_K02, K_K03, K_K05
Pass with a grade based on the following:
- exam results (40%)
- results of self-conducted qualitative analyzes (50%)
- assessment of the correctness of keeping a laboratory diary (5%)
- the degree of compliance with BPH rules and order regulations (5%)
Required grade threshold:
- sufficient: 50 -60%
- sufficient plus: 61 - 65%
- good: 66 – 75%
- good plus: 76 – 80%
very good: 81-100%
Practical placement
Not applicable
Bibliography
1. G. M. Blackburn, M.J. Gait, D. Loakes, D. M. Williams, Nucleic acid in Chemistry and Biology, RSC, 2006.
2. Z. Jóźwiak, G. Bartosz, Biofizyka, PWN, Warszawa, 2005.
3. Z. Kęcki, Podstawy spektroskopii molekularnej, PWN, 1998.
4. A. Grodzicki, Symetria cząsteczek, a ich widma oscylacyjne. Państw. Wydaw. Nauk., 1988
5. F. Alpert, K. Szymański, Spektroskopia w podczerwieni, PWN, 1974.
6. F. A. Cotton, Teoria grup zastosowania w chemii, PWN, 1973.
7. A. Turek, J. Najbar, Fotochemia i spektroskopia optyczna, PWN, 2009.
8. J.R. Lakowicz, Principles of Fluorescence Spectroscopy, Springer, 2006.
9. A. Cygański, Metody spektroskopowe w chemii analitycznej, PWN, 2022.
10. W. Zieliński, A. Rajca, Metody spektroskopowe i ich zastosowanie do identyfikacji związków organicznych, PWN, 1995.
Additional information
Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system: