Bioorganic Chemistry 0600-S2-ChK-ChBO

The lecture covers the following content:
Monosaccharides, disaccharides, oligosaccharides, and polysaccharides - structure, properties, reactions, and modifications of starch and cellulose. Lipids - fatty acids, fats, oils and waxes, terpenes, rubber, steroids. Biosynthesis of fatty acids, terpenes, and cholesterol. Alkaloids, major groups, and their properties, selected methods for synthesizing heterocyclic compounds: pyrroles, pyridines, quinolines, isoquinolines, and indoles. Amino acids: structure, properties, peptide bond, methods of amino acid synthesis. Peptide synthesis methods, protecting groups. Oligopeptides and proteins – examples, properties, and structures. Methods of protein structure analysis.

Laboratory:
1/2. Wagner-Meerwain rearrangement, ester hydrolysis. Synthesis of isoborneol from camphene.
3. Separation of essential oil components using column chromatography
4. Glucose esterification.
5. Isolation of caffeine from tea.

Total student workload

Hours conducted with the participation of teachers: - participation in lectures - 15 h - participation in laboratories - 30 h Time spent on individual student work: - preparation for the laboratory - 5 h - preparation for colloquia - 3 h - preparation for the exam - 20 h - consulting and working with the academic teacher - 2 h

Learning outcomes - knowledge

Student: W1: has in-depth knowledge of the primary branches of chemistry - K_W01 W2: knows the synthesis and characterization of organic and biologically active compounds - K_W03 W3: can properly plan experiments and verify the obtained results - K_W07

Learning outcomes - skills

Student: U1: uses extended knowledge from essential areas of chemistry and applies it in the field of cosmetic chemistry - K_U01 U2: can synthesize and transform natural compounds, isolate them from natural sources, and analyze them - K_U03 U3: searches for information in scientific and popular science magazines and chemical databases in Polish and English; presents the results of work in the form of written reports - K_U05 U4: can search in the literature for synthesis methods and research on the composition and properties of organic and natural compounds - K_U08

Learning outcomes - social competencies

Student: K1: understands the need for further learning; can independently take actions to expand and deepen chemical knowledge - K_K01 K2: can cooperate in a team and solve problems related to scientific research and chemical synthesis - K_K02 K3: is aware of professionalism, appreciation of intellectual honesty, and compliance with professional ethics, both in one's actions and those of other people - K_K05

Teaching methods

Teaching giving methods: - informative (conventional) lecture with multimedia presentations. Didactic searching methods: - laboratory: laboratory classes are related to the program content covered by the lecture. The student synthesizes preparations and isolates natural compounds based on the available instructions and recommended literature.

Expository teaching methods

- informative (conventional) lecture

Exploratory teaching methods

- laboratory

Type of course

compulsory course

Prerequisites

Basic general, analytical, and organic chemistry knowledge at the first level of studies.

Course coordinators

Marek Krzemiński

Assessment criteria

Lecture: written exam – W1-W2, U1, U3, U4, K1, K3
Laboratory – W1-W3, U1-U4, K1-K3
The Bioorganic Chemistry block consists of lecture (15 hours) and laboratory (30 hours).
Lecture – the conditions for passing the exam are:
1) passing all components of the block;
2) obtaining at least 50% of points in the written exam.
Lab: The student is obliged to prepare four preparations, and the results obtained must be prepared in the form of written reports in the laboratory journal, passing three tests (10 points each) covering the scope of knowledge contained in the exercises performed.
Reports are assessed on a point scale of 0 – 10 points, with the following division:
0 – 4 points – description in the laboratory journal of the experiment performed, laboratory work technique, knowledge of the instructions for performing the exercise.
0 – 6 points – the quality of the results obtained, calculation of efficiency, measurement of physicochemical constants, description of the recorded IR spectra, conclusions.
The required threshold for a satisfactory grade is 50%, satisfactory plus - 61%, good - 66%, good plus - 76%, very good - 81%.

Practical placement

Not applicable

Bibliography

Literature in polish:

1. A. Kołodziejczyk, Związki naturalne, Wyd. 2, PWN 2004.
2. J. McMurry, Chemia Organiczna T. 4 i 5, Wyd. 3, PWN, Warszawa, 2007/2010.
3. I. Vogel, Preparatyka organiczna, wyd. 3, Warszawa, WNT, 2006.
4. R. Kasprzykowska, A. S. Kołodziejczyk, K. Stachowiak, E. Jankowska, Preparatyka i analiza związków naturalnych, Wyd. Uniwersytetu Gdańskiego, Gdańsk, 2009.

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 0600-S2-ChK-ChBO in USOSweb