Controlled drug delivery systems 0600-S2-CM-PW-SKDL

Lecture
The lecture's content is devoted to encapsulation methods used in pharmaceutical techniques. The lecture presents the history of the encapsulation of medicinal substances, the current state, and the possibilities of development in modern technologies. It offers the basics of encapsulation technology. He discusses the mechanisms of encapsulation, methods of obtaining capsules, the efficiency of encapsulation, and factors influencing it. It characterizes in detail the polymers used as the shell material of the capsules. Various types of capsules with examples of their use will be presented. The lecture discusses the mechanisms of drug release from capsules.

Laboratory classes:
The student will receive and study drug carriers with controlled release during the laboratory classes using various encapsulation techniques.

Total student workload

1. 10 h - lecture, 20 h - laboratory class, 35 h - consultations 2. 15 h - individual work 3. 20 h - time required to prepare to participate in the assessment process 4. 0 h – internships Total: 100 h (4 ECTS)

Learning outcomes - knowledge

W1: has in-depth knowledge of chemistry, constituting the theoretical basis for education in the field of medical chemistry; knows the main development trends in the use chemical methods in medicine and pharmacy - K_W01. W2: knows and understands in a more profound degree analytical methods and instrumental measurement techniques used in medicine and pharmacy and their importance for the progress of exact and natural sciences, cognition of the world, and human development - K_W03. W3: knows the current development directions and the latest achievements related to medical chemistry - K_W04.

Learning outcomes - skills

U1 - can use the knowledge of chemistry in medicine and pharmacy, properly select analytical and instrumental methods used in medicine - K_U01. U2: can critically evaluate the results of analyzes, discuss measurement errors and apply the appropriate software package for the statistical analysis of the experiment - K_U03.

Learning outcomes - social competencies

K1- can formulate and present opinions on chemical issues in medicine and pharmacy and is aware of the importance of the acquired knowledge in scientific and professional work - K_K01.

Course coordinators

Justyna Kozłowska

Teaching methods

Lecture: Conventional lecture with the use of audiovisual means. Assessment methods: final test checking the knowledge of the subject. Laboratory classes: Practical classes performed individually. Assessment methods: assessment of reports on the performed exercises, test.

Prerequisites

Basic knowledge of general chemistry, organic chemistry, physical chemistry.

Assessment criteria

Final test – W1, W2, W3
Test (laboratory classes) – W1, W2, W3, U1, U2, K1

Pass threshold: 50%
50-60% - 3,
61-65% - 3+,
66-75% - 4,
76-80% - 4+,
81-100% - 5

Bibliography

1.M. Giamberini, S. Fernandez Prieto, B. Tylkowski, Microencapsulation, Innovative Applications, DeGruyter, Berlin, 2015.
2. S. Benita, Microencapsulation: Methods and Industrial Applications, CRC Press, Boca Raton, 2005.
3. M. Mishra, Handbook of Encapsulation and Controlled Release, CRC Press, Boca Raton, 2016.
4. Tylkowski, M. Giamberini, S. Fernandez Prieto, Microencapsulation, De Gruyter, Berlin, Boston, 2020.

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 0600-S2-CM-PW-SKDL in USOSweb