Bioactive compounds in raw materials and herbal medicines 0600-S2-CM-PW/ZB

Lecture program content:
The lecture will provide knowledge on bioactive compounds found in plant raw materials that have therapeutic effects and are currently used in medicine. Methods of isolating these compounds from the plant matrix and methods of their identification will be presented. Additionally, the principles of raw material standardization and methods of quantitative analysis of bioactive compounds will be discussed.
Laboratory program content:
The laboratory is dedicated to familiarizing students with methods of extracting biologically active compounds from raw materials and plant drugs and techniques used in their analysis.
Exercise titles:
1. Spectrophotometric determination of berberine
2. Chromatographic determination of carvacrol
3. Gravimetric determination of silica
4. Spectrophotometric determination of the sum of anthocyanins
5. Fluorimetric determination of salicin
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Term 2023/24Z:

Term 2024/25Z:

Term 2025/26Z:

Total student workload

1. Hours conducted with the participation of teachers (contact hours): - hours conducted as part of the lecture 5h; - hours conducted as part of the laboratory 25h. - consultations and work with an academic teacher 35 h. 2. Individual student work: - preparing the student for laboratory classes 10 h; - preparing reports on completed exercises 25 h; A total of 100 hours/25h = 4 ECTS points

Learning outcomes - knowledge

W1 The student knows the methods of preparing samples of raw materials and plant medicines for analysis. K_W03 W2 Has knowledge of the possibilities of using classical and instrumental methods in the qualitative and quantitative analysis of plant bioactive compounds K_W03 W3 Has knowledge of the directions of development and the latest achievements in the use of plant bioactive compounds in medicine. K_W04

Learning outcomes - skills

U1 Is able to propose a method for determining bioactive components in raw materials and herbal medicines. K_U01 U2 Is able to statistically develop the obtained analysis results and develop reports from the performed analyses. K_U02, K_U04

Learning outcomes - social competencies

K1 Presents opinions on chemical issues in medicine and pharmacy. K_K01 K2 Understands ethical and social aspects of practical use of acquired knowledge and skills. K_K02 K3 Is able to share his/her knowledge K_K03

Teaching methods

Lecture – method of giving – problem lecture. Laboratory – laboratory searching method.

Observation/demonstration teaching methods

- display

Expository teaching methods

- participatory lecture
- informative (conventional) lecture

Exploratory teaching methods

- experimental
- practical

Type of course

elective course

Prerequisites

(in Polish) -

Course coordinators

Marzanna Kurzawa

Assessment criteria

Lecture: credit based on attendance and activity.

Satisfactory - minimum 60% attendance at lectures.

Satisfactory plus - 70% attendance

Good - 80% attendance

Good plus - 90% attendance and activity

Very good - 100% attendance and activity
Laboratory: credit based on points obtained from reports on performed exercises.

For a grade of satisfactory (60-65%)
The student knows the theoretical foundations of analytical methods and is able to describe analyses carried out in the laboratory.

K_W03; K_W04
For a grade of satisfactory plus (65-70%)
The student knows and understands the theoretical foundations of analytical methods and knows the principles of describing chemical analysis carried out in the laboratory.

K_W03; K_W04; K_U01; K_U02;
For a grade of good (70-80%)
Knows the method and understands the theoretical principles and the method of performing the analysis. Is able to plan and independently describe the analysis and draw correct conclusions.

K_W03; K_W04; K_U01; K_U02; K_U04; K_K02
For a grade of good plus (80-90%)
Has full knowledge of the analytical method, understands the principle of working with the appropriate equipment and laboratory glassware. Is able to apply the acquired knowledge to solve new analytical problems.
K_W03; K_W04; K_U01; K_U02; K_U04; K_K01; K_K02; K_K03
For a grade of very good (> 90%)
Has knowledge that goes beyond the thematic scope of the laboratory, acquired independently while working in the library, uses appropriate methods for examining complex matrices and is able to apply them to solve new analytical problems.
K_W03; K_W04; K_U01; K_U02; K_U04; K_K01; K_K02; K_K03

Practical placement

not applicable

Bibliography

Basic literature
1. M. Cichosz, U. Kiełkowska, M. Kurzawa, Skrypt bio-chemiczny, Wydawnictwo UMK, Toruń 2022.
2. B. Klimek red., Analiza fitochemiczna roślinnych substancji leczniczych, Wyd UM Łódź, 2011
3. A. Kołodziejczyk, Naturalne związki organiczne, PWN, Warszawa, 2013
4. D. Hota, Boactive medicinal plants, Gene-Tech Books New Delhi 2007
5. Ed. C. Carkeet K. Grann, R. K. Randolph, D. S. Venzon, S. M. Izzy Phytochemicals Health Promotion and Therapeutic Potential, Taylor & Francis Group, 2013

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 0600-S2-CM-PW/ZB in USOSweb