Toxicology 0600-S2-CKR-T

The lecture covers elements of general toxicology, aspects of specialized toxicology, and toxicological analysis. It will present the goals and tasks of toxicology, as well as the mechanisms of toxic action. The lecture includes an introduction to the toxicity of organic compounds such as pesticides, drugs, psychoactive substances, narcotics, volatile organic compounds (VOCs), and natural poisons.
Students will learn the principles of collecting biological material, environmental samples, and evidence for toxicological studies. The lecture program also includes methods of identification (NMR, MS, IR, UV-Vis spectroscopy) and chromatographic methods for the determination of xenobiotics (GC, HPLC, coupled techniques). Students will be introduced to health and safety rules for working with toxic substances and biological material, as well as methods of providing first aid to poisoned individuals.
The laboratory exercises involve the use of chromatographic techniques for the identification and quantitative determination of xenobiotics, spectroscopic methods for determining the structure of toxins and xenobiotics, specialized toxicology issues, and the principles of evidence sampling.

Total student workload

Number of hours conducted with the participation of an academic teacher (50h): Lectures: 10h Laboratory: 30h Consultations: 10h Student's independent work (75h): Preparation for lectures: 5h Preparation for the exam: 30h Preparation for laboratory: 5h Preparation of laboratory reports: 35h

Learning outcomes - knowledge

W1: Student knows the definitions and terminology used in toxicology. K_W01 W2: Student understands instrumental analysis methods applicable in toxicology. K_W03 W3: Student understands the methods and procedures in toxicological analysis. K_W01

Learning outcomes - skills

U1: Student is able to select the appropriate sample preparation method for a specific matrix and analyzed substance. K_U04, K_U05, K_U06 U2: Student is able to select and conduct chromatographic analysis depending on the type of analyte. K_U04, K_U05, K_U06

Learning outcomes - social competencies

K1 Student is able to work in a team to find a solution to a given research problem. K_K01

Teaching methods

Informative lecture Laboratory exercises

Expository teaching methods

- informative (conventional) lecture
- description

Exploratory teaching methods

- observation
- laboratory

Type of course

compulsory course

Prerequisites

Knowledge of the fundamentals of organic chemistry, analytical chemistry, and instrumental methods at the undergraduate level.

Course coordinators

Andrzej Wolan

Assessment criteria

Lecture: Written exam – W1, W2, W3
Laboratory: Evaluation of reports in the laboratory notebook – U1, U2, K1

Grading scale:

Sufficient (dst): 50–60%
Sufficient+ (dst+): 61–65%
Good (db): 66–75%
Good+ (db+): 76–80%
Very good (bdb): 81–100%

Practical placement

Bibliography

1. Seńczuk W. Toksykologia współczesna, PZWL, Warszawa 2012
2. Gawlik M. Toksykologia: wybrane zagadnienia, Wydaw. Uniwersytetu Jagiellońskiego, Kraków 1999
3. Bogdanik T. Toksykologia kliniczna: Państwowy Zakład Wydawnictw Lekarskich, Warszawa 1988.
4. Tęgowska E., Wosińska A. Skrypt do ćwiczeń z toksykologii
i ekotoksykologii dla studentów Ochrony Środowiska. Wydawnictwo Naukowe UMK, Toruń 2013.
5. Raszeja S., Nasiłowski W Medycyna sądowa – podręcznik dla studentów Państwowy Zakład Wydawnictw Lekarskich, 1990
6. DiMaio V. J. Medycyna Sądowa –Urban&Partner 2008
7. Zieliński W., Rajca A. Metody spektroskopowe i ich zastosowanie do identyfikacji związków organicznych, Wydawnictwo Naukowo Techniczne, 1990.

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 0600-S2-CKR-T in USOSweb