Natural products analysis 0600-S1-Cm-PW7b-IV

Lecture content:
The lecture is intended to familiarize students with compounds of natural origin and methods of their analysis. The lecture will discuss the most important groups of secondary metabolites of plants and methods: sample preparation for analysis, identification, identity testing and quantitative analysis using classical and instrumental methods.
Laboratory content:
The laboratory is dedicated to familiarizing students with methods of collecting and preparing samples for the analysis of natural raw materials and analytical procedures used in their research. Laboratory classes will include methods of collecting and preparing samples for analysis and marking selected components of raw materials of natural origin, including: flavonoids, polyphenols, phenolic acids, alkaloids and antioxidant activity. Titrimetric, electrochemical, spectroscopic and chromatographic methods will be used in the analyses. Most of the exercises are based on standard methods included in Polish and European Standards and the Polish Pharmacopoeia VIII and European Pharmacopoeia 5.0.

Term 2022/23Z:

Lecture content:
The lecture is intended to familiarize students with the methods of analyzing natural products. The lecture will discuss the methods of preparing samples for analysis, identification, identity testing and quantitative analysis using classical and instrumental methods.
Laboratory content:
The laboratory is dedicated to familiarizing students with the methods of collecting and preparing samples for the analysis of natural raw materials and the analytical procedures used in their research. Laboratory classes will include methods of collecting and preparing samples for analysis and marking selected components of natural raw materials, including: flavonoids, polyphenols, phenolic acids, alkaloids, vitamins and selected antinutritional components. Marking antioxidant activity. Titrimetric, electrochemical, spectroscopic and chromatographic methods will be used in the analyses. Most of the exercises are based on standard methods included in Polish and European Standards and the Polish Pharmacopoeia VIII and European Pharmacopoeia 5.0.

Term 2023/24Z:

Term 2024/25Z:

Term 2025/26Z:

Total student workload

1. Hours conducted with the participation of teachers (contact hours): - hours conducted as part of the lecture 10h; - hours conducted as part of the laboratory 35h. - consultations and work with an academic teacher 8 h. 2. Individual student work: - preparing the student for laboratory classes 22 h; - preparing reports on completed exercises 50 h; Total 125 hours/25h = 5 ECTS points

Learning outcomes - knowledge

K1 The student knows the methods of preparing samples of natural products for analysis. K_W01 K2 Has knowledge of the possibilities of using classical and instrumental methods in the qualitative and quantitative analysis of natural products. K_W04, K_W08 K3 Has knowledge of the causes and methods of avoiding errors in quantitative analysis and knowledge of the method of presenting analysis results. K_W02 K4 Defines the basic groups of chemical compounds found in natural products. K_W01

Learning outcomes - skills

U1 The student is able to analyze and solve problems related to the analysis of natural products based on the acquired knowledge. K_U01 U2 Is able to propose a method for marking the components of natural products. K_U05 U3 Is able to statistically develop the obtained analysis results and develop reports from the performed analyses. K_U02 U4 Is able to use equipment used in the qualitative and quantitative analysis of natural products. K_U04

Learning outcomes - social competencies

K1 Is focused on acquiring new knowledge, skills and experiences concerning the analysis of natural products. K_K01 K2 Establishes cooperation in a group. K_K02 K3 Determines priorities in order to plan and implement a specific task. K_K03

Teaching methods

Lecture – method of giving – problem lecture. Laboratory – laboratory searching method.

Expository teaching methods

- informative (conventional) lecture
- problem-based lecture

Exploratory teaching methods

- laboratory

Prerequisites

Credit for Fundamentals of Analytical Chemistry

Course coordinators

Marzanna Kurzawa

Assessment criteria

Lecture: graded based on class attendance and activity.

Criteria.

For a grade of satisfactory (50-60%)
The student defines: basic components of natural products, knows the theoretical foundations of analytical methods and is able to describe the analyses carried out in the laboratory. K_W01; K_W02; K_W04, K_W08
For a grade of satisfactory plus (61-65%)
The student is able to classify the components of natural products. Knows and understands the theoretical foundations of analytical methods and knows the principles of describing the chemical analysis carried out in the laboratory. K_W01; K_W02; K_W04; K_W08
For a grade of good (66-75%)
The student is able to recognize and qualify the hazards associated with the components of natural products. The student is able to propose a methodology for marking individual components of natural products. Knows the method and understands the theoretical principles and the method of performing the analysis. Is able to plan and independently describe the analysis and draw the correct conclusions. K_W01; K_W02; K_W04; K_W08; K_U01; K_U05;
For a grade of good plus (76-80%)
Can apply acquired knowledge to assess the quality of natural products. Has full knowledge of the analytical method, understands the principle of working with the appropriate equipment and laboratory glassware. K_W01; K_W02; K_W04; K_W08; K_U01; K_U05;
For a grade of very good (>80%)
Has knowledge that goes beyond the thematic scope of the lecture, acquired independently while working in the library. K_W01; K_W02; K_W04; K_W08; K_U01; K_U05;

Laboratory: credit with a grade based on reports from the analyses performed
Criteria.
For a grade of satisfactory (50-60%)
The student knows the theoretical foundations of analytical methods and is able to describe the analyses performed in the laboratory.
For a grade of satisfactory plus (61-65%)
The student knows and understands the theoretical foundations of analytical methods and knows the principles of describing chemical analysis carried out in the laboratory.

For a grade of good (66-75%)
Knows the method and understands the theoretical principles and the method of performing the analysis. Can plan and independently describe the analysis and draw correct conclusions.

For a grade of good plus (76-80%)
Has full knowledge of the analytical method, understands the principle of working with the appropriate equipment and laboratory glassware. Can apply the acquired knowledge to solve new analytical problems.

For a grade of very good (>80%)
Has knowledge that goes beyond the thematic scope of the laboratory acquired independently while working in the library, uses appropriate methods of examining complex matrices and can apply them to solve new analytical problems.

Practical placement

not applicable

Bibliography

Basic literature
1. B. Klimek red., Analiza fitochemiczna roślinnych substancji leczniczych, Wyd UM Łódź, 2011
2. A. Kołodziejczyk, Naturalne związki organiczne, PWN, Warszawa, 2013
3. M. Cichosz, U. Kiełkowska, M. Kurzawa, Skrypt bio-chemiczny, Wydawnictwo UMK, 2022.
Additional literature
1. A. Gliszczyńska-Świgło, Przeciwutleniające i proutleniające właściwości wybranych składników żywności jako wyróżnik jej jakości, Wyd UE Poznań, 2010

Term 2022/23Z:

Additional literature:
1. A. Gliszczyńska-Świgło, Przeciwutleniające i proutleniające właściwości wybranych składników żywności jako wyróżnik jej jakości, Wyd UE Poznań, 2010
2. S. Kohlmunzer, Farmakognozja, Wydawnictwo Lekarskie PZWL, Warszawa, 2007

Term 2023/24Z:

Term 2024/25Z:

Term 2025/26Z:

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 0600-S1-Cm-PW7b-IV in USOSweb