Inorganic Chemistry in therapy and diagnostic 0600-S1-CM-PW7c-VI

Lecture combined with discussion
1. Theoretical foundations of coordination chemistry.
2. The role of metals and ligands in biological systems.
3. Characteristics of selected toxic elements and their influence on the human body.
4. Chelatotherapy.
5. Vitamin C, vitamin B12 and B6 vitamins as an example of biological: reducing agents, complexes and biological ligands.
6. Chemotherapy - cancer therapy.
7. Psychotropic drugs. Treatment of indigestion, ulcers. Antibacterial drugs.
8. No - EDRF. The role of NO and NO-secreting compounds in the treatment of heart disease.
9. Chrysotherapy - gold compounds and treatment of RA.
10. Chromium and vanadium compounds and diabetes.
11. Contrast compounds. NMR tomography.
12. Light and metal complexes in medicine. PDT, therapy for jaundice, psoriasis ...
13. Radiopharmaceuticals. PET / SPECT
14. Women who changed science. Nobel Prizes in Chemistry.

Lab:
Synthesis and characterystics of chromium and vanadium complexes; Determination of ASA content in pharmaceutical preparations; Synthesis of copper (II) and iron (III) complexes with ASA and SA and their spectral characteristics; Research on the stability of hydrogen peroxide and the production of peroxygen combinations of selected d-electron metals; Antiseptics - bismuth(III) oxide iodide - synthesis and analysis.

Total student workload

Contact hours with teacher: - participation in lectures – 15 hrs - participation in practical sessions – 30 hrs - consultations – 10 hrs Self-study hours: - preparation for classes/writing reports - 15 hrs - reading literature - 10 hrs - preparation for tests/examination - 20 hrs Altogether: 100 hrs/25 = 4 ECTS

Learning outcomes - knowledge

1. Has knowledge of the main departments of chemistry, uses the appropriate terminology and nomenclature - K_W01 2. Has the knowledge to understand the basic problems related to the subject of the field of study - K_W11 3. Has basic knowledge of biological and chemical sciences used in biomedical research and describes the basic physical, chemical and biological phenomena occurring in a living organism - K_W03 4. Knows the theoretical and practical aspects of methods, techniques and research tools used in chemical and biological analyzes - K_W04

Learning outcomes - skills

1. Can analyze and solve chemical and biological problems based on the acquired knowledge - K_U01 2. Can plan an experiment and use the equipment for the implementation of a specific research task - K_U04

Learning outcomes - social competencies

1. Understands the necessity of continuous improvement and improvement of professional competences - K_K01

Teaching methods

Lecture: Lecture combined with discussion. Lab: Performing planned laboratory exercises, discussion with pairs during the performance of a given task, independent work.

Expository teaching methods

- problem-based lecture
- participatory lecture

Exploratory teaching methods

- laboratory

Prerequisites

The knowledge of general, analytical, inorganic, physical chemistry and mathematics. Knowledge of the English language.

Course coordinators

Olga Impert

Assessment criteria

Written test, final lecture test (60%):;
Tickets and work in pairs - laboratory (40%):.
Written test - K_W01, K_W11, K_W03, K_W04
Short tests - K_U01, K_U04, K_W03, K_W11, K_W01

Bibliography

P. Atkins, T. Overton i in., Shriver&Atkins Inorganic Chemistry, 5 wyd. Oxford University Press 2010;
2. C.E. Housecroft, A.G. Sharpe, „Inorganic Chemistry”, 4 wyd., Person Education Limited 2005;
3. J. R. Gispert, “Coordination Chemistry”, Wiley-VCh 2008;
4. Artykuły publikowane na łamach: Wiadomości Chemicznych, Chemii w Szkole, Journal of Chemical Education, Coordination Chemistry Reviews.

Additional information

Additional information (registration calendar, class conductors, localization and schedules of classes), might be available in the USOSweb system:

Description of 0600-S1-CM-PW7c-VI in USOSweb